USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: CAP1_HUMAN USC-OGP 2-DE database:  CAP1_HUMAN CAP1_HUMAN General information about the entry View entry in simple text format Entry name CAP1_HUMAN Primary accession number Q01518 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Adenylyl cyclase-associated protein 1; Short=CAP 1;. Gene name Name=CAP1 Synonyms=CAP Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0891: pI=6.99; Mw=55266 SPOT OGP-0892: pI=6.86; Mw=55117 Cross-references UniProtKB/Swiss-Prot Q01518; CAP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CAP1_HUMAN Primary accession number Q01518 Secondary accession number(s) Q53HR7 Q5T0S1 Q5T0S2 Q6I9U6 Sequence was last modified on  October 5, 2010 (version 5) Annotations were last modified on  March 15, 2017 (version 170) Name and origin of the protein Description RecName: Full=Adenylyl cyclase-associated protein 1; Short=CAP 1; Gene name Name=CAP1 Synonyms=CAP Encoded on Name=CAP1; Synonyms=CAP Keywords 3D-structure; Acetylation; Actin-binding; Alternative splicing; Cell membrane; Complete proteome; Direct protein sequencing; Isopeptide bond; Membrane; Methylation; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M98474; AAA35648.1; -; mRNA EMBL L12168; AAA35507.1; -; mRNA EMBL BT007152; AAP35816.1; -; mRNA EMBL CR457409; CAG33690.1; -; mRNA EMBL AK222513; BAD96233.1; -; mRNA EMBL AL512599; CAI11021.1; -; Genomic_DNA EMBL AL512599; CAI11022.1; -; Genomic_DNA EMBL BC013963; AAH13963.1; -; mRNA EMBL BC095440; AAH95440.1; -; mRNA CCDS CCDS41309.1; -. [Q01518-1]; . CCDS CCDS81304.1; -. [Q01518-2]; . PIR A48120; A48120; . RefSeq NP_001099000.1; NM_001105530.1; . RefSeq NP_006358.1; NM_006367.3; . RefSeq XP_005270425.1; XM_005270368.1. [Q01518-1]; . RefSeq XP_011538811.1; XM_011540509.1. [Q01518-1]; . RefSeq XP_011538812.1; XM_011540510.1. [Q01518-1]; . RefSeq XP_011538813.1; XM_011540511.1. [Q01518-2]; . RefSeq XP_011538814.1; XM_011540512.1. [Q01518-2]; . RefSeq XP_011538815.1; XM_011540513.2. [Q01518-2]; . RefSeq XP_011538816.1; XM_011540514.1. [Q01518-2]; . RefSeq XP_011538817.1; XM_011540515.1. [Q01518-2]; . RefSeq XP_016855556.1; XM_017000067.1. [Q01518-1]; . RefSeq XP_016855557.1; XM_017000068.1. [Q01518-1]; . RefSeq XP_016855558.1; XM_017000069.1. [Q01518-1]; . RefSeq XP_016855559.1; XM_017000070.1. [Q01518-1]; . RefSeq XP_016855560.1; XM_017000071.1. [Q01518-1]; . RefSeq XP_016855561.1; XM_017000072.1. [Q01518-1]; . UniGene Hs.370581; -; . PDB 1K8F; X-ray; 2.80 A; A/B/C/D=319-475 PDBsum 1K8F; -; . ProteinModelPortal Q01518; -; . SMR Q01518; -; . BioGrid 115750; 52; . DIP DIP-62063N; -; . IntAct Q01518; 7; . MINT MINT-3024327; -; . STRING 9606.ENSP00000361878; -; . iPTMnet Q01518; -; . PhosphoSitePlus Q01518; -; . SwissPalm Q01518; -; . BioMuta CAP1; -; . DMDM 308153681; -; . OGP Q01518; -; . REPRODUCTION-2DPAGE IPI00639931; -; . EPD Q01518; -; . MaxQB Q01518; -; . PaxDb Q01518; -; . PeptideAtlas Q01518; -; . PRIDE Q01518; -; . Ensembl ENST00000340450; ENSP00000344832; ENSG00000131236. [Q01518-2]; . Ensembl ENST00000372792; ENSP00000361878; ENSG00000131236. [Q01518-1]; . Ensembl ENST00000372797; ENSP00000361883; ENSG00000131236. [Q01518-1]; . Ensembl ENST00000372798; ENSP00000361884; ENSG00000131236. [Q01518-2]; . Ensembl ENST00000372802; ENSP00000361888; ENSG00000131236. [Q01518-2]; . Ensembl ENST00000372805; ENSP00000361891; ENSG00000131236. [Q01518-1]; . GeneID 10487; -; . KEGG hsa:10487; -; . UCSC uc001cey.5; human. [Q01518-1]; . CTD 10487; -; . DisGeNET 10487; -; . GeneCards CAP1; -; . HGNC HGNC:20040; CAP1; . HPA HPA030124; -; . MalaCards CAP1; -; . neXtProt NX_Q01518; -; . OpenTargets ENSG00000131236; -; . PharmGKB PA399; -; . eggNOG KOG2675; Eukaryota; . eggNOG ENOG410XPXJ; LUCA; . GeneTree ENSGT00390000017955; -; . HOGENOM HOG000206192; -; . HOVERGEN HBG003080; -; . InParanoid Q01518; -; . KO K17261; -; . OMA CHTYLSK; -; . OrthoDB EOG091G0DLX; -; . PhylomeDB Q01518; -; . TreeFam TF313791; -; . Reactome R-HSA-114608; Platelet degranulation; . Reactome R-HSA-428890; Role of Abl in Robo-Slit signaling; . Reactome R-HSA-6798695; Neutrophil degranulation; . ChiTaRS CAP1; human; . EvolutionaryTrace Q01518; -; . GeneWiki CAP1; -; . GenomeRNAi 10487; -; . PRO PR:Q01518; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000131236; -; . CleanEx HS_CAP1; -; . ExpressionAtlas Q01518; baseline and differential; . Genevisible Q01518; HS; . GO GO:0035578; C:azurophil granule lumen; TAS:Reactome; . GO GO:0030864; C:cortical actin cytoskeleton; IBA:GO_Central; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005615; C:extracellular space; IEA:Ensembl; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; . GO GO:0003779; F:actin binding; IBA:GO_Central; . GO GO:0008179; F:adenylate cyclase binding; IBA:GO_Central; . GO GO:0008154; P:actin polymerization or depolymerization; IBA:GO_Central; . GO GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc; . GO GO:0001667; P:ameboidal-type cell migration; IEA:Ensembl; . GO GO:0000902; P:cell morphogenesis; IBA:GO_Central; . GO GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl; . GO GO:0007165; P:signal transduction; TAS:ProtInc; . Gene3D 2.160.20.70; -; 1; . InterPro IPR001837; Adenylate_cyclase-assoc_CAP; . InterPro IPR013912; Adenylate_cyclase-assoc_CAP_C; . InterPro IPR013992; Adenylate_cyclase-assoc_CAP_N; . InterPro IPR017901; C-CAP_CF_C-like; . InterPro IPR016098; CAP/MinC_C; . InterPro IPR028415; CAP1; . InterPro IPR028417; CAP_CS_C; . InterPro IPR018106; CAP_CS_N; . InterPro IPR006599; CARP_motif; . PANTHER PTHR10652; PTHR10652; 1; . PANTHER PTHR10652:SF16; PTHR10652:SF16; 1; . Pfam PF08603; CAP_C; 1; . Pfam PF01213; CAP_N; 1; . SMART SM00673; CARP; 2; . SUPFAM SSF101278; SSF101278; 1; . SUPFAM SSF69340; SSF69340; 1; . PROSITE PS51329; C_CAP_COFACTOR_C; 1; . PROSITE PS01088; CAP_1; 1; . PROSITE PS01089; CAP_2; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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